Killers creating new life: caspases drive apoptosis-induced proliferation in tissue repair and disease

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Role of caspases in apoptosis and disease.

Apoptosis, a genetically governed process of eliminating cells in response to a variety of stimuli provides protection against cancer and viral infections as well as maintains homeostasis. Recent studies using both molecular and cloning approaches, and in vitro systems have identified a class of highly specific proteases, termed caspases, that appear to have an important role in apoptotic execu...

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ژورنال

عنوان ژورنال: Cell Death & Differentiation

سال: 2017

ISSN: 1350-9047,1476-5403

DOI: 10.1038/cdd.2017.47